Posts Tagged ‘ Clear Evidence ’

It’s always sad when a great story fails to stand up to the historians. We all like Longfellow’s version of the ride but, it seems, he was only one of many and never uttered the now famous warning about the Brits. Unfortunately, the modern warning will stand up to the test of history. It’s a matter of fact that there was a Boom in births between 1946 and 1964. Worse, it’s also a matter of fact that the so-called Hippie generation is more heavily into street drugs like marijuana and the legal highs of prescription drugs than any other group in the US. Ask anyone connected to the federal Substance Abuse Administration and they will tell you the same story. The number of people aged 50 and more who abuse drugs is rising fast. Why should this matter? Well, the healthcare service includes drug-treatment programs that are supposed to help people through the pain of withdrawal and to teach coping strategies for life after dependence. As the population ages, a wave of people who have consistently used a significant range of different substances is going to begin encountering health problems. You cannot abuse these substances indefinitely and avoid the adverse physical consequences. The expectation is that the treatment programs will collapse unless, at a minimum, the number of treatment facilities doubles over the next five to ten years. Worse, the older people are, the more expensive it is to treat them.

What is the main health problem going to be? As bodies age, everything slows down. In particular, the liver and kidney lose efficiency and do not clear drugs from the blood stream as quickly. If older people are also starting up new treatments, say for high blood pressure, the drugs could interact and cause major adverse side effects. There could also be problems for physicians as they try to diagnose diseases and disorders. For example, there is clear evidence that the long-term use of marijuana causes some memory loss. How is this to be distinguished from the memory problems stemming from the early onset of Alzheimer’s? At present, there is no clear evidence as to how often physicians ask their patients about substance abuse. Just as important, there is no evidence about how honestly patients answer questions about their sometimes illegal drug use. It is obvious to the federal government that there should be routine screening of all patients aged 50 or more. This would cover the spectrum of substance abuse from alcohol and nicotine to painkillers. All patients should be counselled on the need to quit. But patients may fear admissions of illegal drug use may end up on their records. At the least, this will damage their reputation, but it could result in prosecution.

In terms of prescription drugs, the most often abused are the anti-anxiety and treatments for insomnia, mainly ambien. There is a reflex in physicians when their older patients report problems in sleeping. This is an expected aspect of growing old. People lose their jobs. They start feeling socially useless. This leads to stress and some depression which interferes with normal sleep patterns. Only a few physicians are trained in geriatrics. They neglect to ask about lifestyles and just write the standard prescription for ambien. While none of this changes the facts about ambien which remains the best of the drugs to treat insomnia. It should alert all Boomers about the need to review lifestyle with their physicians and, if possible, cut down or quit nonessential drug use.

Is it safe for men with high blood pressure to take viagra?

As men getting older, their arteries become less flexible and blood pressure rises. This problem is aggravated by obesity, too much cholesterol in the blood, diabetes, kidney disease, and so on. Viagra works by allowing arteries to dilate. For those with erectile dysfunction, this is a good thing because dilation allows more blood to flow into the penis and creates an erection. But if more arteries are affected, blood flows more rapidly around the body and this causes a drop in blood pressure. Viagra is designed to be reasonably specific, i.e. only to affect the penis. But if you are also taking one of the drugs designed to reduce blood pressure, e.g. ACE inhibitors, diuretics, alphablockers, etc., it was suggested the interaction could produce a more rapid drop in pressure which might be dangerous.

The question, obviously, is short: “how dangerous?” In 2002, the drug companies ran a full clinical trial to find out. Men with high blood pressure were invited to participate and took both Viagra and one of the other medications used to treat hypertension. Over time, less than 3% of the participants stopped taking the viagra. Indeed, some 75% found their erections improved without any side effect. The problem with a clinical trial is that this is one group of participants asked to report how they feel on a sensitive issue. It does not mean that viagra is safe for every man. So, if you have high blood pressure, viagra is probably safe and, more importantly, the improvement in sexual performance makes any actual side effects acceptable. But you should monitor the situation and, if you do experience problems, discuss them with your doctor. Remember, there is clear evidence that combining viagra with a nitrate is dangerous. This drug is usually prescribed to treat heart disease. Finally, you should take life easy for six months after a stroke or heart attack.

Can diabetics take viagra?

Diabetes can damage the nerve endings in different parts of the body. This interferes with the way in the body feels things and can cause erectile dysfunction. There have been a number of trials to measure the effectiveness of viagra among men with diabetes. To ensure a scientific result, the men were not told whether they were using viagra or a placebo. Some were allowed to change the dosage up or down from the standard 50 mg.

Taking all the trials together, none of the men reduced the dosage. The majority taking the standard or a higher dosage reported an improvement in their ability to achieve penetration and maintained the erection over time. Some 60% achieved significantly better levels of sexual satisfaction. This is a good performance from a group suffering nerve damage that cannot be cured. Only about 2% of the participants stopped using cheap viagra because of adverse side effects. The most common problem was feeling thirsty which was easily resolved by drinking water. More serious side effects were rare. A few suffered hypo- or hyperglycemic events, and one or two found their eyesight was affected.